2413035-43-3
Chemical Structure
SJF-0661
- CAS No.: 2413035-43-3
- Formula:C51H57F2N9O7S2
- Molecular Weight:1010.18
InChIKey: MBCAVOCJJAQHHT-NYNRYUPBSA-N
SMILES: O=C(C1=C(C(NS(CCC)(=O)=O)=CC=C1F)F)C2=CNC3=NC=C(C4=CC=C(N5CCN(CC5)CC(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@@H](C6)O)C(NCC7=CC=C(C8=C(C)N=CS8)C=C7)=O)=O)=O)C=C4)C=C23
Biological Activity: SJF-0661 is a variant of the von Hippel-Lindau (VHL) protein ligand with no targeted degradation ability and can be used as a control reagent for the VHL ubiquitin ligase ligand. SJF-0661 is a variant obtained by inverting the stereocenter of the key hydroxyproline group in the VHL ligand[1].
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SJF-0661 | SJF-0661 is a variant of the von Hippel-Lindau (VHL) protein ligand with no targeted degradation ability and can be used as a control reagent for the VHL ubiquitin ligase ligand. SJF-0661 is a variant obtained by inverting the stereocenter of the key hydroxyproline group in the VHL ligand. | |||||||||||||||||||||
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Keywords
