2414254-49-0

Gly-Cyclopropane-Exatecan Chemical Structure
2414254-49-0

Chemical Structure

Gly-Cyclopropane-Exatecan

  • CAS No.: 2414254-49-0
  • Formula:C32H34FN5O7
  • Molecular Weight:619.64

InChIKey: CEFSJFYTDCGHFB-XXCFHSPASA-N

SMILES: NCC(NCOC(C1CC1)C(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O

Biological Activity: Gly-Cyclopropane-Exatecan involves in the synthesis of anti-B7-H4 ADC, containing Exatecan (HY-13631), a DNA Topoisomerase I inhibitor. Gly-Cyclopropane-Exatecan participated in the formation of the ADC hu2F7-Exatecan (compound 34), which showed antitumor activity in vivo and in vitro[1].

Cat. No. Product Name Purity Description Pricing
HY-148696A 		Gly-Cyclopropane-Exatecan Gly-Cyclopropane-Exatecan involves in the synthesis of anti-B7-H4 ADC, containing Exatecan (HY-13631), a DNA Topoisomerase I inhibitor. Gly-Cyclopropane-Exatecan participated in the formation of the ADC hu2F7-Exatecan (compound 34), which showed antitumor activity in vivo and in vitro.
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