2416927-21-2
2416927-21-2
Chemical Structure
Dalvotoclax
- CAS No.: 2416927-21-2
- Formula:C45H47ClF3N7O8S
- Molecular Weight:938.41
SMILES: O=C(C(C=CC(N1CCN(CC(CCC(C)(C2)C)=C2C3=C(Cl)C=C(C(F)(F)F)C=C3)CC1)=C4)=C4OC5=CN=C6NC=CC6=C5)NS(C7=CC([N+]([O-])=O)=C(NC[C@H]8COCCO8)C=C7)(=O)=O
Biological Activity: Dalvotoclax (Example 8) is a selective inhibitor of BCL-2. Dalvotoclax has good liver microsomal stability. Dalvotoclax inhibits the activity of anti-apoptotic BCL-2 protein and anti-apoptotic BCL-XL protein. Dalvotoclax can be studied in research for B cell leukemia[1].
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Dalvotoclax | Dalvotoclax (Example 8) is a selective inhibitor of BCL-2. Dalvotoclax has good liver microsomal stability. Dalvotoclax inhibits the activity of anti-apoptotic BCL-2 protein and anti-apoptotic BCL-XL protein. Dalvotoclax can be studied in research for B cell leukemia. | |||||||||||||||||||||
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References
Keywords
