2417955-18-9
Chemical Structure
Osivelotor
Synonym(s): GBT-601; GBT-021601
- CAS 番号: 2417955-18-9
- Formula:C20H22N2O6
- Molecular Weight:386.40
IUPAC Name: Nw-(methyl-d3)-L-arginine
InChIKey: NIWBSQAKKNNWBT-AWEZNQCLSA-N
SMILES: O=C(C1=C(N=CC=C1)CCO)N2[C@@H](COCC2)COC3=C(C(O)=CC=C3)C=O
Biological Activity: Osivelotor is an orally effective small molecule. Osivelotor is an allosteric regulator of deoxyhemoglobin S (HbS). Osivelotor increases the affinity of HbS to oxygen, inhibits HbS polymerization, and thus prevents erythrocyte sickling in the blood. Osivelotor can be used for research of sickle cell disease (SCD) [1] [2].
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Osivelotor | 98.10% | Osivelotor is an orally effective small molecule. Osivelotor is an allosteric regulator of deoxyhemoglobin S (HbS). Osivelotor increases the affinity of HbS to oxygen, inhibits HbS polymerization, and thus prevents erythrocyte sickling in the blood. Osivelotor can be used for research of sickle cell disease (SCD) . | ||||||||||||||||||||
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Keywords
