2418549-30-9
2418549-30-9
Chemical Structure
EGFR-IN-54
- CAS No.: 2418549-30-9
- Formula:C17H14N4O4S3
- Molecular Weight:434.51
IUPAC Name: 4-(3-(benzo[d][1,3]dioxol-5-yl)thioureido)-N-(thiazol-2-yl)benzenesulfonamide
InChIKey: AKJZGCUHFBZJNV-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(NC(NC2=CC=C(OCO3)C3=C2)=S)C=C1)(NC4=NC=CS4)=O
Biological Activity: EGFR-IN-54 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 1.623 µM. EGFR-IN-54 shows cytotoxic activity against cancer cell lines[1].
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EGFR-IN-54 | EGFR-IN-54 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 1.623 µM. EGFR-IN-54 shows cytotoxic activity against cancer cell lines. | |||||||||||||||||||||
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References
Keywords
