2427608-43-1
Chemical Structure
JAK1-IN-11
- CAS No.: 2427608-43-1
- Formula:C26H36N6O4S
- Molecular Weight:528.67
IUPAC Name: 1-((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)-N-((1-(2-((R)-1-hydroxyethyl)imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(5H)-yl)piperidin-4-yl)methyl)methanesulfonamide
InChIKey: CMZLROFEPZYUSV-LBISXTPBSA-N
SMILES: C[C@@H](O)C1=NC2=CNC3=NC=CC3=C2N1N(CC4)CCC4CNS(C[C@@]56C(C)(C)[C@@](CC6)([H])CC5=O)(=O)=O
Biological Activity: JAK1-IN-11 (compound 11) is a potent inhibitor of JAK，with IC50s of 0.02 nM (JAK1)，and 0.44 nM (JAK2)，respectively. JAK1-IN-11 has high selectivity against JAK1 over JAK2[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JAK1-IN-11 | 98.27% | JAK1-IN-11 (compound 11) is a potent inhibitor of JAK，with IC50s of 0.02 nM (JAK1)，and 0.44 nM (JAK2)，respectively. JAK1-IN-11 has high selectivity against JAK1 over JAK2. | ||||||||||||||||||||
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Keywords
