2446160-73-0
Chemical Structure
Azido-PEG3-SS-NHS
- CAS No.: 2446160-73-0
- Formula:C15H24N4O7S2
- Molecular Weight:436.50
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9-trioxa-12,13-dithiahexadecan-16-oate
InChIKey: GULGJNLQJQCHEW-UHFFFAOYSA-N
SMILES: O=C(ON1C(CCC1=O)=O)CCSSCCOCCOCCOCCN=[N+]=[N-]
Biological Activity: Azido-PEG3-SS-NHS is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG3-SS-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azido-PEG3-SS-NHS | 95.0% | Azido-PEG3-SS-NHS is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG3-SS-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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Keywords