2454488-02-7
Chemical Structure
KRAS G12C inhibitor 42
- CAS No.: 2454488-02-7
- Formula:C33H34FN7O2
- Molecular Weight:579.67
IUPAC Name: 2-((S)-1-acryloyl-4-(8-fluoro-7-(8-methylnaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)pyrido[4,3-d]pyrimidin-4-yl)piperazin-2-yl)acetonitrile
InChIKey: JCIQWPCUVDTKAS-ZEQRLZLVSA-N
SMILES: N#CC[C@@H]1N(C(C=C)=O)CCN(C2=C(C=NC(C3=C4C(C)=CC=CC4=CC=C3)=C5F)C5=NC(OC[C@H]6N(C)CCC6)=N2)C1
Biological Activity: KRAS G12C inhibitor 42 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 42 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2020146613A1, compound 10)[1].
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KRAS G12C inhibitor 42 | KRAS G12C inhibitor 42 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 42 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2020146613A1, compound 10). | |||||||||||||||||||||
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Keywords
