2454636-44-1
Chemical Structure
Antibacterial agent 107
- CAS No.: 2454636-44-1
- Formula:C39H55N9O7
- Molecular Weight:761.91
IUPAC Name: (S)-N-((S)-1-amino-5-guanidino-1-oxopentan-2-yl)-5-guanidino-2-(2-(5-((3-methylbut-2-en-1-yl)oxy)-2-((E)-3-(4-((3-methylbut-2-en-1-yl)oxy)phenyl)acryloyl)phenoxy)acetamido)pentanamide
InChIKey: GAWMDBNTWDIAKW-CBIVFTRNSA-N
SMILES: C/C(C)=C\COC1=CC=C(C=C1)/C=C/C(C2=C(C=C(C=C2)OC/C=C(C)/C)OCC(N[C@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)=O
Biological Activity: Antibacterial agent 107 (compound 14) is a potent antibacterial agent. Antibacterial agent 107 shows potent antibacterial activity against Gram-positive bacteria, with a MIC of 1.56 μg/mL (MRSA). Antibacterial agent 107 exhibits low hemolytic activity, high membrane selectivity, and rapid bactericidal activity. Antibacterial agent 107 shows effective in vivo efficacy in the murine model of bacterial keratitis caused by Staphylococcus aureus ATCC29213[1].
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Antibacterial agent 107 | Antibacterial agent 107 (compound 14) is a potent antibacterial agent. Antibacterial agent 107 shows potent antibacterial activity against Gram-positive bacteria, with a MIC of 1.56 μg/mL (MRSA). Antibacterial agent 107 exhibits low hemolytic activity, high membrane selectivity, and rapid bactericidal activity. Antibacterial agent 107 shows effective in vivo efficacy in the murine model of bacterial keratitis caused by Staphylococcus aureus ATCC29213. | |||||||||||||||||||||
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Keywords
