2457317-40-5
Chemical Structure
CDK8-IN-10
- CAS No.: 2457317-40-5
- Formula:C25H15ClF3N5O3
- Molecular Weight:525.87
IUPAC Name: 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(5-oxo-6-(pyridin-4-yl)-5,6-dihydrobenzo[b]pyrido[3,2-f][1,4]oxazepin-9-yl)urea
InChIKey: NQHGDUGVQSAKOR-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(N2C3=CC=NC=C3)C(OC4=NC=CC=C4C2=O)=C1)NC5=CC=C(Cl)C(C(F)(F)F)=C5
Biological Activity: CDK8-IN-10 (compound 2) is a potent, selective cyclin-dependent kinase (CDK8) inhibitor with an IC50 value of 8.25 nM. CDK8-IN-10 can be used for research of cancer[1].
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CDK8-IN-10 | CDK8-IN-10 (compound 2) is a potent, selective cyclin-dependent kinase (CDK8) inhibitor with an IC50 value of 8.25 nM. CDK8-IN-10 can be used for research of cancer. | |||||||||||||||||||||
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Keywords