2458163-94-3
2458163-94-3
Chemical Structure
PI3K-IN-34
- CAS No.: 2458163-94-3
- Formula:C23H22N6O3
- Molecular Weight:430.46
IUPAC Name: (E)-2-(2-(3-hydroxybenzylidene)hydrazinyl)-4-(4-methoxyphenyl)-6-morpholinopyrimidine-5-carbonitrile
InChIKey: AOESDOSNOQSBDO-MFKUBSTISA-N
SMILES: N#CC1=C(N2CCOCC2)N=C(N/N=C/C3=CC=CC(O)=C3)N=C1C4=CC=C(OC)C=C4
Biological Activity: PI3K-IN-34 (Compound 6g) is a highly selective PI3K inhibitor with IC50 values of 11.73, 6.09 and 11.18 μM for PI3K-α、PI3K-β and PI3K-δ , respectively. PI3K-IN-34 arrests cell cycle at G2/M phase and induces apoptosis. PI3K-IN-34 can be used in leukemia research[1].
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PI3K-IN-34 | PI3K-IN-34 (Compound 6g) is a highly selective PI3K inhibitor with IC50 values of 11.73, 6.09 and 11.18 μM for PI3K-α、PI3K-β and PI3K-δ , respectively. PI3K-IN-34 arrests cell cycle at G2/M phase and induces apoptosis. PI3K-IN-34 can be used in leukemia research. | |||||||||||||||||||||
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References
Keywords
