2460651-09-4
Chemical Structure
Antitubercular agent-27
- CAS No.: 2460651-09-4
- Formula:C14H8BrN3O3
- Molecular Weight:346.14
IUPAC Name: N-(4-bromo-1,3-dioxoisoindolin-2-yl)isonicotinamide
InChIKey: PTAYSFASQUXRSS-UHFFFAOYSA-N
SMILES: O=C(NN(C(C1=C2C=CC=C1Br)=O)C2=O)C3=CC=NC=C3
Biological Activity: Antitubercular agent-27 (compound 1) is a potent antitubercular agent with an IC50 value of 3.2 µM, an MIC value of 7.8 µM, an IC90 value of 7.0 µM. Antitubercular agent-27 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-27 shows effective intracellular antimycobacterial activity and low cytotoxicity[1].
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Antitubercular agent-27 | Antitubercular agent-27 (compound 1) is a potent antitubercular agent with an IC50 value of 3.2 µM, an MIC value of 7.8 µM, an IC90 value of 7.0 µM. Antitubercular agent-27 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-27 shows effective intracellular antimycobacterial activity and low cytotoxicity. | |||||||||||||||||||||
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Keywords
