2482764-71-4
Chemical Structure
Antileishmanial agent-12
- CAS No.: 2482764-71-4
- Formula:C25H21N3O4
- Molecular Weight:427.45
IUPAC Name: 3-(2-methylprop-1-en-1-yl)-1,4-dioxo-1,4-dihydronaphthalen-2-yl 3-(1-phenyl-1H-1,2,3-triazol-4-yl)propanoate
InChIKey: OQTMIDIYWCZMCR-UHFFFAOYSA-N
SMILES: O=C(OC(C1=O)=C(/C=C(C)\C)C(C2=C1C=CC=C2)=O)CCC3=CN(C4=CC=CC=C4)N=N3
Biological Activity: Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent. Antileishmanial agent-12 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC50 values of 14.9, 21.3 and 9.3 μM, respectively[1].
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Antileishmanial agent-12 | Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent. Antileishmanial agent-12 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC50 values of 14.9, 21.3 and 9.3 μM, respectively. | |||||||||||||||||||||
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Keywords