2487649-61-4
Chemical Structure
Axl-IN-10
- CAS No.: 2487649-61-4
- Formula:C27H25N7O2
- Molecular Weight:479.53
IUPAC Name: N-(4-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl)-2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo[1,5-a]pyridine-3-carboxamide
InChIKey: TUEAZGCOJDXLNO-UHFFFAOYSA-N
SMILES: CN1C=C(C2=C1N=CN=C2N)C3=CC=C(C=C3)NC(C4=C5CCCCN5N(C4=O)C6=CC=CC=C6)=O
Biological Activity: Axl-IN-10 (Example 1) is a potent AXL inhibitor, with an IC50 of 5 nM. Axl-IN-10 has excellent transmembrane properties.Axl-IN-10 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-10 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals[1].
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Axl-IN-10 | Axl-IN-10 (Example 1) is a potent AXL inhibitor, with an IC50 of 5 nM. Axl-IN-10 has excellent transmembrane properties.Axl-IN-10 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-10 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals. | |||||||||||||||||||||
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Keywords
