24886-52-0

Azaphen free base Chemical Structure
24886-52-0

Chemical Structure

Azaphen free base

Synonym(s): Azafen free base; Pipofezin; Pipofezine

  • CAS No.: 24886-52-0
  • Formula:C16H19N5O
  • Molecular Weight:297.35

IUPAC Name: 5-methyl-3-(4-methylpiperazin-1-yl)-5H-benzo[b]pyridazino[4,3-e][1,4]oxazine

InChIKey: SDYYIRPAZHJOLM-UHFFFAOYSA-N

SMILES: CN1C2=C(C=CC=C2)OC3=NN=C(N4CCN(CC4)C)C=C31

Biological Activity: Azaphen free base (Azafen free base) is an orally active tricyclic antidepressant that inhibits the reuptake of serotonin and monoamines, regulates the 5-HT2c receptor, and exerts sedative, antidepressant and anxiolytic effects. Azaphen free base increases the bioavailability of serotonin in the synaptic cleft, does not block muscarinic receptors or affect monoamine oxidase activity, and binds to the human serotonin transporter via salt bridges, π-stacking, π-cation and hydrophobic interactions. Azaphen free base can be used in studies related to depression[1][2][3].

Cat. No. Product Name Purity Description Pricing
HY-I0135 		Azaphen free base Azaphen free base (Azafen free base) is an orally active tricyclic antidepressant that inhibits the reuptake of serotonin and monoamines, regulates the 5-HT2c receptor, and exerts sedative, antidepressant and anxiolytic effects. Azaphen free base increases the bioavailability of serotonin in the synaptic cleft, does not block muscarinic receptors or affect monoamine oxidase activity, and binds to the human serotonin transporter via salt bridges, π-stacking, π-cation and hydrophobic interactions. Azaphen free base can be used in studies related to depression.
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