2490396-99-9
Chemical Structure
ERK1/2 inhibitor 4
- CAS No.: 2490396-99-9
- Formula:C28H31ClFN5O5S
- Molecular Weight:604.09
IUPAC Name: (R)-2-(2-(5-chloro-2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-4-oxo-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-N-((S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl)propanamide
InChIKey: JPJKPWPSJCCCAQ-IVZQSRNASA-N
SMILES: O=C1C2=C(CCN1[C@H](C)C(N[C@@H](C3=CC(OC)=CC(F)=C3)CO)=O)SC(C4=NC(NC5CCOCC5)=NC=C4Cl)=C2
Biological Activity: ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 5 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2020238776A1)[1].
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ERK1/2 inhibitor 4 | ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 5 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2020238776A1). | |||||||||||||||||||||
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Keywords