2494195-61-6
Chemical Structure
Isoleucyl tRNA synthetase-IN-2
- CAS No.: 2494195-61-6
- Formula:C22H33N5O8S
- Molecular Weight:527.59
IUPAC Name: ((2R,3S,4R,5R)-3,4-dihydroxy-5-(2-(4-phenyl-1H-1,2,3-triazol-1-yl)ethoxy)tetrahydro-2H-pyran-2-yl)methyl (L-isoleucyl)sulfamate
InChIKey: UZLLFMFZKAOOHK-SUYSKIEASA-N
SMILES: O[C@H]([C@@H]([C@H](OC1)COS(NC([C@@H](N)[C@@H](C)CC)=O)(=O)=O)O)[C@@H]1OCCN2C=C(C3=CC=CC=C3)N=N2
Biological Activity: Isoleucyl tRNA synthetase-IN-2 (compound 36a) is a potent and selective isoleucyl-tRNA synthetase (IleRS) inhibitor, with a Ki,app of 114 nM[1].
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Isoleucyl tRNA synthetase-IN-2 | Isoleucyl tRNA synthetase-IN-2 (compound 36a) is a potent and selective isoleucyl-tRNA synthetase (IleRS) inhibitor, with a Ki,app of 114 nM. | |||||||||||||||||||||
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Keywords