251577-09-0
251577-09-0
Chemical Structure
FTI-2148
- CAS No.: 251577-09-0
- Formula:C24H28N4O3S
- Molecular Weight:452.57
IUPAC Name: (5-((((1H-imidazol-5-yl)methyl)amino)methyl)-2'-methyl-[1,1'-biphenyl]-2-carbonyl)-L-methionine
InChIKey: KULAYTGUTXCHSV-QFIPXVFZSA-N
SMILES: CSCC[C@@H](C(O)=O)NC(C1=CC=C(CNCC2=CN=CN2)C=C1C3=CC=CC=C3C)=O
Biological Activity: FTI-2148 is a RAS C-terminal mimetic dual farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 1.4 nM and 1.7 μM, respectively[1].
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FTI-2148 | FTI-2148 is a RAS C-terminal mimetic dual farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 1.4 nM and 1.7 μM, respectively. | |||||||||||||||||||||
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References
Keywords
