2522594-49-4
Chemical Structure
Antitumor agent-55
- CAS No.: 2522594-49-4
- Formula:C32H34N6O4S
- Molecular Weight:598.72
IUPAC Name: 3,4,5-trimethoxy-N-(1-(5-methyl-2-((naphthalen-1-ylmethyl)thio)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidin-3-yl)benzamide
InChIKey: QDVCZPRTGHJWFT-UHFFFAOYSA-N
SMILES: O=C(NC1CN(C2=CC(C)=NC3=NC(SCC4=C5C=CC=CC5=CC=C4)=NN23)CCC1)C6=CC(OC)=C(OC)C(OC)=C6
Biological Activity: Antitumor agent-55 (compound 5q) is a potent antitumor agent. Antitumor agent-55 effectively inhibits PC3, with an IC50 of 0.91 μM. Antitumor agent-55 effectively inhibits the colony formation, suppresses the cell migration in PC3. Antitumor agent-55 induces G1/S phase arrest and apoptosis in PC3[1].
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Antitumor agent-55 | Antitumor agent-55 (compound 5q) is a potent antitumor agent. Antitumor agent-55 effectively inhibits PC3, with an IC50 of 0.91 μM. Antitumor agent-55 effectively inhibits the colony formation, suppresses the cell migration in PC3. Antitumor agent-55 induces G1/S phase arrest and apoptosis in PC3. | |||||||||||||||||||||
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Keywords
