2541690-15-5
2541690-15-5
Chemical Structure
TGFβRI-IN-5
- CAS No.: 2541690-15-5
- Formula:C16H12N2O6
- Molecular Weight:328.28
IUPAC Name: 2-(N-acetyl-4-nitrobenzamido)benzoic acid
InChIKey: FJNGYVMTOCTQFD-UHFFFAOYSA-N
SMILES: CC(N(C1=CC=CC=C1C(O)=O)C(C2=CC=C(C=C2)[N+]([O-])=O)=O)=O
Biological Activity: TGFβRI-IN-5 (Compound 4b) is a potent inhibitor of TGFβRI with an IC50 of 0.08 μM. TGFβRI-IN-5 displays amazing anticancer activity 5–7 times that of reference agent against all the tested cell lines. TGFβRI-IN-5 enhances apoptosis and arrested G2/M phase of cell cycle[1].
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TGFβRI-IN-5 | TGFβRI-IN-5 (Compound 4b) is a potent inhibitor of TGFβRI with an IC50 of 0.08 μM. TGFβRI-IN-5 displays amazing anticancer activity 5–7 times that of reference agent against all the tested cell lines. TGFβRI-IN-5 enhances apoptosis and arrested G2/M phase of cell cycle. | |||||||||||||||||||||
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References
Keywords
