2549160-15-6

LASSBio-2052 Chemical Structure
2549160-15-6

Chemical Structure

LASSBio-2052

  • CAS No.: 2549160-15-6
  • Formula:C23H20F3N3O3
  • Molecular Weight:443.42

InChIKey: HKEFPBIUONACLH-CCVNUDIWSA-N

SMILES: O=C(N/N=C/C1=CC=C(C(F)(F)F)C=C1)C2=CC=CC=C2NCC3=CC=C(OC)C(O)=C3

Biological Activity: LASSBio-2052 is a derivative of N-acylhydrazone with antitumor activity against hepatocellular carcinoma (HCC). LASSBio-2052 inhibits HCC cells HepG2 and Hep3B, with IC50 of 18 and 41 μM. LASSBio-2052 arrests the cell cycle at G2/M phase, through downregulation of FOXM1. LASSBio-2052 induces apoptosis in HCC cells[1].

Cat. No. Product Name Purity Description Pricing
HY-161617 		LASSBio-2052 LASSBio-2052 is a derivative of N-acylhydrazone with antitumor activity against hepatocellular carcinoma (HCC). LASSBio-2052 inhibits HCC cells HepG2 and Hep3B, with IC50 of 18 and 41 μM. LASSBio-2052 arrests the cell cycle at G2/M phase, through downregulation of FOXM1. LASSBio-2052 induces apoptosis in HCC cells.
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