2568276-81-1

PROTAC SMARCA2/4 degrader-15 Chemical Structure
2568276-81-1

Chemical Structure

PROTAC SMARCA2/4 degrader-15

  • CAS No.: 2568276-81-1
  • Formula:C50H55N11O5S
  • Molecular Weight:922.11

InChIKey: SECMIPOEDDAVSM-YMNQWFGKSA-N

SMILES: NC1=C(C=C(C2=C(C=CC=C2)O)N=N1)N3CC4N(C5=NC=C(C6=CC=C(C=C6)CC(N[C@@H](C(C)(C)C)C(N7[C@@H](C[C@H](C7)O)C(NCC8=CC=C(C9=C(N=CS9)C)C=C8)=O)=O)=O)C=N5)C(CC4)C3

Biological Activity: PROTAC SMARCA2/4-degrader-15 (Compound I-335) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2/4-degrader-15 degrades SMARCA2 in A549 with DC50 <100 nM, degrades SMARCA4 in MV411 with DC50 <100 nM[1]

Cat. No. Product Name Purity Description Pricing
HY-163868 		PROTAC SMARCA2/4 degrader-15 PROTAC SMARCA2/4-degrader-15 (Compound I-335) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2/4-degrader-15 degrades SMARCA2 in A549 with DC50 <100 nM, degrades SMARCA4 in MV411 with DC50 <100 nM
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