2619531-95-0
2619531-95-0
Chemical Structure
DHODH-IN-25
- CAS No.: 2619531-95-0
- Formula:C22H19ClF5N3O5
- Molecular Weight:535.85
InChIKey: LJSREXLRPZHXMV-VUWPPUDQSA-N
SMILES: O=C(N1C(CO)CCC1=O)NC2=CC(O[C@@H](C)C(F)(F)F)=C(C(NC3=C(F)C=CC=C3Cl)=O)C=C2F
Biological Activity: DHODH-IN-25 (Compound 25) is an orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 value of 5.4 nM for human DHODH. DHODH-IN-25 can be used for the study of acute myeloid leukemia (AML)[1].
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DHODH-IN-25 | DHODH-IN-25 (Compound 25) is an orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 value of 5.4 nM for human DHODH. DHODH-IN-25 can be used for the study of acute myeloid leukemia (AML). | |||||||||||||||||||||
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References
Keywords
