26289-39-4
26289-39-4
Chemical Structure
S-(2,4-Dinitrophenyl)glutathione
- CAS No.: 26289-39-4
- Formula:C16H19N5O10S
- Molecular Weight:473.41
IUPAC Name: N5-((R)-1-((carboxymethyl)amino)-3-((2,4-dinitrophenyl)thio)-1-oxopropan-2-yl)-L-glutamine
InChIKey: FXEUKVKGTKDDIQ-UWVGGRQHSA-N
SMILES: OC([C@@H](N)CCC(N[C@H](C(NCC(O)=O)=O)CSC1=C(C=C(C=C1)[N+]([O-])=O)[N+]([O-])=O)=O)=O
Biological Activity: S-(2,4-Dinitrophenyl)glutathione is a substrate for glutathione-S-transferase. (2,4-Dinitrophenyl)glutathione can be used as an irreversible glutathione reductase inhibitor with an Ki value of 30 µM[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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S-(2,4-Dinitrophenyl)glutathione | 99.89% | S-(2,4-Dinitrophenyl)glutathione is a substrate for glutathione-S-transferase. (2,4-Dinitrophenyl)glutathione can be used as an irreversible glutathione reductase inhibitor with an Ki value of 30 µM. | ||||||||||||||||||||
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References
- [1]. Yokooji T, et al. Site-specific bidirectional efflux of 2,4-dinitrophenyl-S-glutathione, a substrate of multidrug resistance-associated proteins, in rat intestine and Caco-2 cells. J Pharm Pharmacol. 2007 Apr;59(4):513-20. [Content Brief]
- [2]. Bilzer M, et al. Interaction of a glutathione S-conjugate with glutathione reductase. Kinetic and X-ray crystallographic studies. Eur J Biochem. 1984 Jan 16;138(2):373-8. [Content Brief]
Keywords
