2632259-92-6
Chemical Structure
ZW4864 free base
- CAS No.: 2632259-92-6
- Formula:C33H42N6O3
- Molecular Weight:570.72
IUPAC Name: (R)-N-(4-(1H-pyrazol-4-yl)benzyl)-N-cyclopropyl-1-(3-((2-methyl-1-oxo-1-(piperazin-1-yl)propan-2-yl)oxy)phenyl)piperidine-3-carboxamide
InChIKey: DEGJSKLSOCKWSF-AREMUKBSSA-N
SMILES: O=C([C@H]1CN(C2=CC=CC(OC(C)(C)C(N3CCNCC3)=O)=C2)CCC1)N(C4CC4)CC5=CC=C(C6=CNN=C6)C=C5
Biological Activity: ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction (β catenin/BCL9 PPI) inhibitor. ZW4864 (free base) inhibits β catenin/BCL9 PPI with a Ki value of 0.76 μM and an IC50 value of 0.87 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ZW4864 free base | 99.42% | ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction (β catenin/BCL9 PPI) inhibitor. ZW4864 (free base) inhibits β catenin/BCL9 PPI with a Ki value of 0.76 μM and an IC50 value of 0.87 μM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
