2637485-12-0
Chemical Structure
Lp-PLA2-IN-9
- CAS No.: 2637485-12-0
- Formula:C25H19ClF5N3O4
- Molecular Weight:555.88
IUPAC Name: 3-((4-(3-chloro-4-(trifluoromethoxy)phenoxy)-3,5-difluorobenzyl)oxy)-7,8-dihydro-1H,6H,9H-6,8a-ethanopyrrolo[1',2':3,4]imidazo[1,2-c]pyrimidin-1-one
InChIKey: WLAIANJMCBAVRC-UHFFFAOYSA-N
SMILES: O=C1N=C(C=C2N1CC34N2C(CC4)CC3)OCC5=CC(F)=C(C(F)=C5)OC6=CC=C(C(Cl)=C6)OC(F)(F)F
Biological Activity: Lp-PLA2-IN-9 (compound 17), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.1 for rhLp-PLA2. Lp-PLA2-IN-9 has the potential for neurodegenerative related diseases research[1].
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Lp-PLA2-IN-9 | Lp-PLA2-IN-9 (compound 17), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.1 for rhLp-PLA2. Lp-PLA2-IN-9 has the potential for neurodegenerative related diseases research. | |||||||||||||||||||||
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Keywords
