2637485-13-1
Chemical Structure
Lp-PLA2-IN-6
- CAS No.: 2637485-13-1
- Formula:C25H21F5N4O3
- Molecular Weight:520.45
IUPAC Name: 3-((3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzyl)oxy)-6,7,8,9-tetrahydro-1H,10H-6,9a-ethanopyrido[1',2':3,4]imidazo[1,2-c]pyrimidin-1-one
InChIKey: LMSKSPWBYRMBRO-UHFFFAOYSA-N
SMILES: O=C1N=C(C=C2N1CC34N2C(CC4)CCC3)OCC5=CC(F)=C(C(F)=C5)OC6=CC(C(F)(F)F)=NC=C6
Biological Activity: Lp-PLA2-IN-6 (compound 18), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.0 for rhLp-PLA2. Lp-PLA2-IN-6 has the potential for neurodegenerative related diseases research[1].
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Lp-PLA2-IN-6 | Lp-PLA2-IN-6 (compound 18), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.0 for rhLp-PLA2. Lp-PLA2-IN-6 has the potential for neurodegenerative related diseases research. | |||||||||||||||||||||
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Keywords
