2641054-59-1
Chemical Structure
LRRK2-IN-4
- CAS No.: 2641054-59-1
- Formula:C25H29ClF2N6O2
- Molecular Weight:518.99
IUPAC Name: (3S,4S)-4-(4-(6-chloro-2-((1-((S)-2,2-difluorocyclopropyl)-5-methyl-1H-pyrazol-4-yl)amino)quinazolin-7-yl)piperidin-1-yl)-4-methyltetrahydrofuran-3-ol
InChIKey: VFCYOTBJVABSBY-ZDXQCDESSA-N
SMILES: FC1([C@](N2C(C)=C(C=N2)NC3=NC4=C(C=C(C(C5CCN([C@@]6([C@@H](COC6)O)C)CC5)=C4)Cl)C=N3)([H])C1)F
Biological Activity: LRRK2-IN-4 is a potent, selective, CNS-penetran and orally active leucine-rich repeat kinase 2 (LRRK2) inhobitor with an IC50 of 2.6 nM. LRRK2-IN-4 has the potential for the research of Parkinson’s disease[1].
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LRRK2-IN-4 | LRRK2-IN-4 is a potent, selective, CNS-penetran and orally active leucine-rich repeat kinase 2 (LRRK2) inhobitor with an IC50 of 2.6 nM. LRRK2-IN-4 has the potential for the research of Parkinson’s disease. | |||||||||||||||||||||
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Keywords
