1. Autophagy
  2. LRRK2
  3. LRRK2-IN-4

LRRK2-IN-4 

Cat. No.: HY-144074
Handling Instructions

LRRK2-IN-4 is a potent, selective, CNS-penetran and orally active leucine-rich repeat kinase 2 (LRRK2) inhobitor with an IC50 of 2.6 nM. LRRK2-IN-4 has the potential for the research of Parkinson’s disease.

For research use only. We do not sell to patients.

LRRK2-IN-4 Chemical Structure

LRRK2-IN-4 Chemical Structure

CAS No. : 2641054-59-1

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Description

LRRK2-IN-4 is a potent, selective, CNS-penetran and orally active leucine-rich repeat kinase 2 (LRRK2) inhobitor with an IC50 of 2.6 nM. LRRK2-IN-4 has the potential for the research of Parkinson’s disease[1].

IC50 & Target

IC50: 2.6 nM (LRRK2)[1]

In Vivo

LRRK2-IN-4 (compound 24) (p.o.) shows good oral bioavailability in male Wistar-Han rats (F=64%), male beagle dogs (F=65%)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

518.99

Formula

C25H29ClF2N6O2

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
LRRK2-IN-4
Cat. No.:
HY-144074
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