2642-98-0
2642-98-0
Chemical Structure
6-Aminochrysene
Synonym(s): 6-Chrysenamine
- CAS No.: 2642-98-0
- Formula:C18H13N
- Molecular Weight:243.30
IUPAC Name: chrysen-6-amine
InChIKey: KIVUHCNVDWYUNP-UHFFFAOYSA-N
SMILES: NC1=C2C=CC=CC2=C3C(C4=CC=CC=C4C=C3)=C1
Biological Activity: 6-Aminochrysene (6-Aminochrysene) is an aromatic amine used as a chemotherapeutic agent in the treatment of splenomegaly, myeloid leukemia, and breast cancer. 6-Aminochrysene is activated by CYP450 in rat liver[1][2][3].
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6-Aminochrysene | 99.71% | 6-Aminochrysene (6-Aminochrysene) is an aromatic amine used as a chemotherapeutic agent in the treatment of splenomegaly, myeloid leukemia, and breast cancer. 6-Aminochrysene is activated by CYP450 in rat liver. | ||||||||||||||||||||
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6-Aminochrysene (Standard) | ≥98% | 6-Aminochrysene (Standard) is the analytical standard of 6-Aminochrysene (HY-108315). This product is intended for research and analytical applications. 6-Aminochrysene (6-Aminochrysene) is an aromatic amine used as a chemotherapeutic agent in the treatment of splenomegaly, myeloid leukemia, and breast cancer. 6-Aminochrysene is activated by CYP450 in rat liver. | ||||||||||||||||||||
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References
- [1]. Yamazaki H, et al. Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes. Carcinogenesis. 1993 Jul;14(7):1271-8. [Content Brief]
- [2]. Russo R, et al. Effects of 6-aminochrysene on liver microsomal enzyme activity. Xenobiotica. 1976 Apr;6(4):201-5. [Content Brief]
- [3]. Lambelin G, et al. Carcinogenicity of 6-aminochrysene in mice. Eur J Cancer. 1975 May;11(5):327-34. [Content Brief]
