264618-44-2

SSR 146977 Chemical Structure
264618-44-2

Chemical Structure

SSR 146977

  • CAS No.: 264618-44-2
  • Formula:C35H42Cl2N4O2
  • Molecular Weight:621.64

IUPAC Name: (R)-3-(1-(3-(1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl)propyl)-4-phenylpiperidin-4-yl)-1,1-dimethylurea

InChIKey: XWPBINGFFFZAOZ-UMSFTDKQSA-N

SMILES: O=C(N(C)C)NC1(CCN(CC1)CCC[C@]2(CN(CCC2)C(C3=CC=CC=C3)=O)C4=CC=C(C(Cl)=C4)Cl)C5=CC=CC=C5

Biological Activity: SSR 146977 is a potent and selective antagonist of the tachykinin NK3 receptor. SSR 146977 inhibits the binding of radioactive neurokinin B to NK3 receptors in Chinese hamster ovary cells, with a Ki of 0.26 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-116822 		SSR 146977 SSR 146977 is a potent and selective antagonist of the tachykinin NK3 receptor. SSR 146977 inhibits the binding of radioactive neurokinin B to NK3 receptors in Chinese hamster ovary cells, with a Ki of 0.26 nM.
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