2648851-27-6
2648851-27-6
Chemical Structure
PD-1/PD-L1-IN-18
- CAS No.: 2648851-27-6
- Formula:C33H32BrCl2N3O4
- Molecular Weight:685.43
IUPAC Name: 4-((2-(benzo[c][1,2,5]oxadiazol-5-ylmethoxy)-4-((2-bromo-[1,1'-biphenyl]-3-yl)methoxy)-5-chlorobenzyl)amino)cyclohexan-1-ol hydrochloride
InChIKey: NLRBJRMQHYWLTE-UHFFFAOYSA-N
SMILES: ClC1=C(OCC2=CC=CC(C3=CC=CC=C3)=C2Br)C=C(OCC4=CC5=NON=C5C=C4)C(CNC6CCC(CC6)O)=C1.Cl
Biological Activity: PD-1/PD-L1-IN-18 (Compound L31) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-18 blocks PD-1/PD-L1 with the IC50 of 1.054 μM. Antitumor Activity[1].
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PD-1/PD-L1-IN-18 | PD-1/PD-L1-IN-18 (Compound L31) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-18 blocks PD-1/PD-L1 with the IC50 of 1.054 μM. Antitumor Activity. | |||||||||||||||||||||
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References
Keywords
