2653338-55-5
Chemical Structure
Thalidomide-4-O-C8-Br
- CAS No.: 2653338-55-5
- Formula:C21H25BrN2O5
- Molecular Weight:465.34
InChIKey: AUXQVFUVNQLUND-UHFFFAOYSA-N
SMILES: BrCCCCCCCCOC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O
Biological Activity: Thalidomide-4-O-C8-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C8-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-15 (HY-181309)[1].
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Thalidomide-4-O-C8-Br | Thalidomide-4-O-C8-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C8-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-15 (HY-181309). | |||||||||||||||||||||
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Keywords