2654821-07-3
2654821-07-3
Chemical Structure
PROTAC EGFR degrader 16
- CAS No.: 2654821-07-3
- Formula:C48H48F2N10O6S
- Molecular Weight:931.02
InChIKey: GCMGHESATZAFCJ-RTAOZKFSSA-N
SMILES: O=C(NC1=NC=CS1)C(C2=C(CCC3)N3C=N2)N(CC4=C5C=C(C6=CC=C(N(C7)CC87CN(C(CC9(O)CCN(C%10=CC=C(N[C@H](CC%11)C(NC%11=O)=O)C=C%10F)CC9)=O)C8)C=C6)C=C4F)C5=O
Biological Activity: PROTAC EGFR degrader 16 is a selective EGFR PROTAC degrader with a DC50 value of < 50 nM. PROTAC EGFR degrader 16 can be used for the study of EGFR-driven cancerssuch as non-small cell lung cancer[1].
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PROTAC EGFR degrader 16 | PROTAC EGFR degrader 16 is a selective EGFR PROTAC degrader with a DC50 value of < 50 nM. PROTAC EGFR degrader 16 can be used for the study of EGFR-driven cancerssuch as non-small cell lung cancer. | |||||||||||||||||||||
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