265986-98-9
Chemical Structure
BIIB 513
- CAS No.: 265986-98-9
- Formula:C19H25N5O8S2
- Molecular Weight:515.56
IUPAC Name: N-carbamimidoyl-4-(4-(furan-2-carbonyl)piperazin-1-yl)-3-(methylsulfonyl)benzamide methanesulfonate
InChIKey: CIZHNWRBNREPCL-UHFFFAOYSA-N
SMILES: O=C(NC(N)=N)C1=CC=C(N2CCN(C(C3=CC=CO3)=O)CC2)C(S(=O)(C)=O)=C1.CS(=O)(O)=O
Biological Activity: BIIB 513 is an inhibitor of NHE 1 that protects against myocardial ischemia. BIIB 513 inhibits acid load recovery with an IC50 of 27 nmol/L in cells expressing wild-type NHE 1 under acute acid load[1].
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BIIB 513 | BIIB 513 is an inhibitor of NHE 1 that protects against myocardial ischemia. BIIB 513 inhibits acid load recovery with an IC50 of 27 nmol/L in cells expressing wild-type NHE 1 under acute acid load. | |||||||||||||||||||||
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Keywords