2660014-14-0
Chemical Structure
KRAS G12C inhibitor 40
- CAS No.: 2660014-14-0
- Formula:C34H36ClFN10O2
- Molecular Weight:671.17
IUPAC Name: 2-((S)-1-((E)-3-(1H-1,2,4-triazol-1-yl)acryloyl)-4-(7-(8-chloro-7-fluoronaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)piperazin-2-yl)acetonitrile
InChIKey: BLVBQVLTXVPOLH-LPMFOMBZSA-N
SMILES: N#CC[C@@H]1N(C(/C=C/N2N=CN=C2)=O)CCN(C3=C4C(CN(C5=C6C(Cl)=C(F)C=CC6=CC=C5)CC4)=NC(OC[C@H]7N(C)CCC7)=N3)C1
Biological Activity: KRAS G12C inhibitor 40 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 40 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2021129824A1, compound 70)[1].
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KRAS G12C inhibitor 40 | KRAS G12C inhibitor 40 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 40 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2021129824A1, compound 70). | |||||||||||||||||||||
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Keywords
