2663787-92-4
Chemical Structure
RORγt agonist 2
- CAS No.: 2663787-92-4
- Formula:C30H30F3N3O4S
- Molecular Weight:585.64
IUPAC Name: N-((S)-2-cyano-1-(4-(ethylsulfonyl)phenyl)ethyl)-3-isopropyl-4-(4-(trifluoromethyl)phenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxamide
InChIKey: PYNADGCIKYWLSV-PVCWFJFTSA-N
SMILES: CC(C1N(C2=CC=C(C=C2)C(F)(F)F)C3=CC=C(C(N[C@H](C4=CC=C(C=C4)S(CC)(=O)=O)CC#N)=O)C=C3OC1)C
Biological Activity: RORγt agonist 2 is a potent agonist of RORγt. RORγt agonist 2 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 2 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136339A1, compound 17)[1].
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RORγt agonist 2 | RORγt agonist 2 is a potent agonist of RORγt. RORγt agonist 2 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 2 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136339A1, compound 17). | |||||||||||||||||||||
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Keywords