2673278-10-7
Chemical Structure
RORγt inhibitor 2
- CAS No.: 2673278-10-7
- Formula:C31H33F5N2O7S
- Molecular Weight:672.66
IUPAC Name: 4-((2S,4S)-2-((difluoromethoxy)methyl)-4-(4-(trifluoromethoxy)phenoxy)pyrrolidin-1-yl)-N-((S)-1-(4-(ethylsulfonyl)phenyl)-3-hydroxypropyl)benzamide
InChIKey: RGAXAFMCYKMXAH-WSHBGFIESA-N
SMILES: FC(F)OC[C@H]1N(C2=CC=C(C=C2)C(N[C@H](C3=CC=C(C=C3)S(CC)(=O)=O)CCO)=O)C[C@H](C1)OC4=CC=C(C=C4)OC(F)(F)F
Biological Activity: RORγt inhibitor 2 (Compound 119) is a potent RORγt inhibitor with an IC50 of 9.2 nM. RORγt inhibitor 2 can be used for the research of cancer, inflammation or autoimmune diseases mediated by RORγt[1].
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RORγt inhibitor 2 | RORγt inhibitor 2 (Compound 119) is a potent RORγt inhibitor with an IC50 of 9.2 nM. RORγt inhibitor 2 can be used for the research of cancer, inflammation or autoimmune diseases mediated by RORγt. | |||||||||||||||||||||
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Keywords