2679825-27-3
2679825-27-3
Chemical Structure
Ac-VLPE-FMK
Synonym(s): Ac-Val-Leu-Pro-Glu(OMe)-CH2F
- CAS No.: 2679825-27-3
- Formula:C25H41FN4O7
- Molecular Weight:528.61
IUPAC Name: methyl (S)-4-((S)-1-(acetyl-L-valyl-L-leucyl)pyrrolidine-2-carboxamido)-6-fluoro-5-oxohexanoate
InChIKey: MDAFONIYDVLMOY-OZIGNCPNSA-N
SMILES: O=C(N(CCC1)[C@@H]1C(N[C@H](C(CF)=O)CCC(OC)=O)=O)[C@H](CC(C)C)NC([C@H](C(C)C)NC(C)=O)=O
Biological Activity: Ac-VLPE-FMK, a tetrapeptidyl mono-fluoromethyl ketone (m-FMK), is a Cat-B and Cat-L inhibitor. Ac-VLPE-FMK can be used for the research of cancer aggressiveness[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ac-VLPE-FMK | 99.0% | Ac-VLPE-FMK, a tetrapeptidyl mono-fluoromethyl ketone (m-FMK), is a Cat-B and Cat-L inhibitor. Ac-VLPE-FMK can be used for the research of cancer aggressiveness. | ||||||||||||||||||||
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References
- [1]. Rudzińska M, et, al. Cysteine Cathepsins Inhibition Affects Their Expression and Human Renal Cancer Cell Phenotype. Cancers (Basel). 2020 May 21;12(5):1310. [Content Brief]
- [2]. Citarella A, et, al. Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry. Molecules. 2020 Sep 3;25(17):4031. [Content Brief]
Keywords
