2683008-37-7
Chemical Structure
OARV-771
- CAS No.: 2683008-37-7
- Formula:C49H59ClN8O8S2
- Molecular Weight:987.62
IUPAC Name: 2-(3-(2-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)propoxy)ethyl 2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
InChIKey: CWTFXHWWWKKEQI-QQRWPDCKSA-N
SMILES: CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(OCCOCCCOCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@H](C4)O)C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)=O)=O)=O)C7=NN=C(C)N27
Biological Activity: OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC50s of 6, 1, and 4 nM for Brd4, Brd2 and Brd3, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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OARV-771 | 98.77% | OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC50s of 6, 1, and 4 nM for Brd4, Brd2 and Brd3, respectively. | ||||||||||||||||||||
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Keywords
