2684258-54-4
Chemical Structure
RET-IN-13
- CAS No.: 2684258-54-4
- Formula:C32H33F4N5O3
- Molecular Weight:611.63
IUPAC Name: 2-(6-(6,7-dimethoxyquinolin-3-yl)pyridin-3-yl)-N-(4-((4-ethylpiperazin-1-yl)methyl)-2-fluoro-5-(trifluoromethyl)phenyl)acetamide
InChIKey: ZZWZYEZSFZRFRF-UHFFFAOYSA-N
SMILES: O=C(CC1=CC=C(C2=CN=C3C=C(C(OC)=CC3=C2)OC)N=C1)NC4=C(F)C=C(CN5CCN(CC5)CC)C(C(F)(F)F)=C4
Biological Activity: RET-IN-13 (compound 1), a quinoline compound, is a potent RET inhibitor with IC50s of 0.5 nM, 0.9 nM for RET (WT) and RET (V804M), respectively. RET-IN-13 has the potential for tumors or intestinal diseases related to abnormal activation of RET research[1].
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RET-IN-13 | RET-IN-13 (compound 1), a quinoline compound, is a potent RET inhibitor with IC50s of 0.5 nM, 0.9 nM for RET (WT) and RET (V804M), respectively. RET-IN-13 has the potential for tumors or intestinal diseases related to abnormal activation of RET research. | |||||||||||||||||||||
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Keywords
