2687960-02-5
Chemical Structure
SAH-13C10
- CAS No.: 2687960-02-5
- Formula:C413C10H20N6O5S
- Molecular Weight:394.34
IUPAC Name: S-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl-13C5)-3,4-dihydroxytetrahydrofuran-2-yl-2,3,4,5-13C4)methyl-13C)-L-homocysteine
InChIKey: ZJUKTBDSGOFHSH-JIXUBOHWSA-N
SMILES: O[13C@H]1[13C@]([H])(N2[13C]3=N[13CH]=N[13C](N)=[13C]3N=[13CH]2)O[13C@H]([13CH2]SCC[C@@H](C(O)=O)N)[13C@H]1O
Biological Activity: SAH-13C10 is the 13C labeled SAH[1]. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[2]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM[3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SAH-13C10 | 99.90% | SAH-13C10 is the 13C labeled SAH. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM. | ||||||||||||||||||||
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SAH (Standard) | 97.22% | SAH (Standard) is the analytical standard of SAH. This product is intended for research and analytical applications. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM. | ||||||||||||||||||||
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SAH-d4 | 98.9% | SAH-d4 is the deuterium labeled SAH. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM. | ||||||||||||||||||||
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SAH | 99.90% | SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM. | ||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. DE LA HABA G, et al. The enzymatic synthesis of S-adenosyl-L-homocysteine from adenosine and homocysteine. J Biol Chem. 1959 Mar;234(3):603-8. [Content Brief]
- [3]. Li F, et al. A Radioactivity-Based Assay for Screening Human m6A-RNA Methyltransferase, METTL3-METTL14 Complex, and Demethylase ALKBH5. Biomol Screen. 2016 Mar21(3):290-7. [Content Brief]
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