26904-64-3
26904-64-3
Chemical Structure
Oxysophocarpine
- CAS No.: 26904-64-3
- Formula:C15H22N2O2
- Molecular Weight:262.35
IUPAC Name: (4R,41S,7aS,13aR,13bR)-10-oxo-2,3,6,7,7a,8,10,13,13a,13b-decahydro-1H,5H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4(41H)-oxide
InChIKey: QMGGMESMCJCABO-JARXUMMXSA-N
SMILES: O=C1C=CC[C@]2([H])[C@@]3([H])CCC[N@@+]4([O-])[C@@]3([H])[C@](CCC4)([H])CN21
Biological Activity: Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides.?Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems[1]. Oxysophocarpine inhibits the?growth?and?metastasis?of ?oral?squamous?cell?carcinoma?(OSCC)[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Oxysophocarpine | 99.59% | Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides.?Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems. Oxysophocarpine inhibits the?growth?and?metastasis?of ?oral?squamous?cell?carcinoma?(OSCC). | ||||||||||||||||||||
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Oxysophocarpine (Standard) | ≥98% | Oxysophocarpine (Standard) is the analytical standard of Oxysophocarpine. This product is intended for research and analytical applications. Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides. Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems. Oxysophocarpine inhibits the growth and metastasis of oral squamous cell carcinoma (OSCC). | ||||||||||||||||||||
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References
- [1]. Xu T, et al. Oxysophocarpine induces anti-nociception and increases the expression of GABAAα1 receptors in mice.Mol Med Rep. 2013 Jun;7(6):1819-25. [Content Brief]
- [2]. Liu, R., Peng, J., Wang, H., et al. Oxysophocarpine retards the growth and metastasis of oral squamous cell carcinoma by targeting the Nrf2/HO-1 axis. Cell Physiol. Biochem. 49(5), 1717-1733 (2018). [Content Brief]
