2692623-94-0
Chemical Structure
Propionyl-L-carnitine-d3 hydrochloride
- No. CAS: 2692623-94-0
- Formula:C10H17D3ClNO4
- Molecular Weight:256.74
IUPAC Name: (R)-3-((propanoyl-3,3,3-d3)oxy)-4-(trimethylammonio)butanoate hydrochloride
InChIKey: KTFMPDDJYRFWQE-SPMMGKNWSA-N
SMILES: [2H]C([2H])([2H])CC(O[C@H](CC([O-])=O)C[N+](C)(C)C)=O.Cl
Biological Activity: Propionyl-L-carnitine-d3 (hydrochloride) is deuterium labeled Propionyl-L-carnitine. Propionyl-L-carnitine is a carnitine derivative and has a high affinity for muscular carnitine transferase. Propionyl-L-carnitine increases cellular carnitine content, thereby allowing free fatty acid transport into the mitochondria. Propionyl-L-carnitine alleviates the symptoms of PAD through a metabolic pathway, thereby improving exercise performance[1][2].
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Propionyl-L-carnitine-d3 hydrochloride | 99.9% | Propionyl-L-carnitine-d3 (hydrochloride) is deuterium labeled Propionyl-L-carnitine. Propionyl-L-carnitine is a carnitine derivative and has a high affinity for muscular carnitine transferase. Propionyl-L-carnitine increases cellular carnitine content, thereby allowing free fatty acid transport into the mitochondria. Propionyl-L-carnitine alleviates the symptoms of PAD through a metabolic pathway, thereby improving exercise performance. | ||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Victor Kamoen, et al. Propionyl-L-carnitine for intermittent claudication. Cochrane Database Syst Rev. 2021 Dec 26;12(12):CD010117. [Content Brief]