2692624-13-6
2692624-13-6
Chemical Structure
Heneicosapentaenoic acid-d6
- CAS No.: 2692624-13-6
- Formula:C21H26D6O2
- Molecular Weight:322.51
IUPAC Name: (6Z,9Z,12Z,15Z,18Z)-henicosa-6,9,12,15,18-pentaenoic-2,2,3,3,4,4-d6 acid
InChIKey: OQOCQFSPEWCSDO-HDCHGOIWSA-N
SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC([2H])(C([2H])(C([2H])(C(O)=O)[2H])[2H])[2H]
Biological Activity: Heneicosapentaenoic acid-d6 is the deuterium labeled Heneicosapentaenoic acid[1].
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Heneicosapentaenoic acid-d6 | Heneicosapentaenoic acid-d6 is the deuterium labeled Heneicosapentaenoic acid. | |||||||||||||||||||||
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Heneicosapentaenoic acid | Heneicosapentaenoic Acid (HPA) is a 21:5 omega-3 fatty acid found in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA), except that a carbon is extended at the carboxy terminus, placing the first double bond at the δ6 position. HPA can be used to study the importance of double bond position in omega-3 fatty acids. It incorporates phospholipids and triacylglycerols in vivo with the same efficiency as EPA and docosahexaenoic acid, and exhibits a strong inhibitory effect on the synthesis of arachidonic acid from linoleic acid. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but retains the ability to rapidly inactivate PGHS. | |||||||||||||||||||||
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References
