2718125-83-6
2718125-83-6
Chemical Structure
LE01
- CAS No.: 2718125-83-6
- Formula:C55H61FN10O14
- Molecular Weight:1105.13
SMILES: O=C(C=C1)N(CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCCN(C)C(OCC(N[C@H]3CCC4=C5C3=C6C(C(N7C6)=CC([C@@](O)(CC)C(OC8)=O)=C8C7=O)=NC5=CC(F)=C4C)=O)=O)=O)=O)=O)=O)=O)C1=O
Biological Activity: LE01 is a drug-linker conjugate for ADC. LE01 contains a ADC linker and a DNA topoisomerase I inhibitor DXd (HY-13631D). LE01 can be used to synthesize HER2-targeting ADC (HER2-LE01)[1].
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LE01 | LE01 is a drug-linker conjugate for ADC. LE01 contains a ADC linker and a DNA topoisomerase I inhibitor DXd (HY-13631D). LE01 can be used to synthesize HER2-targeting ADC (HER2-LE01). | |||||||||||||||||||||
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References
Keywords
