2730027-86-6
Chemical Structure
HSD17B13-IN-36
- CAS No.: 2730027-86-6
- Formula:C20H17F2N3O4S
- Molecular Weight:433.43
InChIKey: HJJXORHVLICVQH-UHFFFAOYSA-N
SMILES: O=S1(CCN(CC1)C2=CC=C(C=C2)C3=NC(OC4=C(C(O)=C(C=C4)F)F)=CC=N3)=O
Biological Activity: HSD17B13-IN-36 (compound 116) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM? estradiol? as substrates. HSD17B13-IN-36? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis)[1].
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HSD17B13-IN-36 | HSD17B13-IN-36 (compound 116) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM? estradiol? as substrates. HSD17B13-IN-36? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis). | |||||||||||||||||||||
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Keywords