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Cat. No.: HY-157663

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HSD17B13-IN-36

HSD17B13-IN-36 (compound 116) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC₅₀ of ＜ 0.1 μM? estradiol? as substrates. HSD17B13-IN-36? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis).

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CAS No.: 2730027-86-6
Formule: C₂₀H₁₇F₂N₃O₄S
Masse moléculaire:433.43

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

HSD17B13-IN-36 Chemical Structure

CAS No.: 2730027-86-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform 17β-HSD :

17β-HSD5/AKR1C3

Chemical Information

CAS No. 2730027-86-6
Masse moléculaire 433.43
Formule C₂₀H₁₇F₂N₃O₄S
SMILES

O=S1(CCN(CC1)C2=CC=C(C=C2)C3=NC(OC4=C(C(O)=C(C=C4)F)F)=CC=N3)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Inipharm, Inc. Preparation of substituted phenoxypyridines and phenoxypyrimidines as HSD17B13 inhibitors and uses thereof. World Intellectual Property Organization, WO2021211974 A1 2021-10-21

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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HSD17B13-IN-36

Voir tous les produits spécifiques à Isoform 17β-HSD

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

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HSD17B13-IN-36 Related Classifications

HY-157663 Related Classifications

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