2735721-00-1

KRAS G12C inhibitor 23 Chemical Structure
2735721-00-1

Chemical Structure

KRAS G12C inhibitor 23

  • CAS No.: 2735721-00-1
  • Formula:C32H32FN5O3
  • Molecular Weight:553.63

IUPAC Name: (S)-1-(4-acryloyl-2-methylpiperazin-1-yl)-11-fluoro-4-(2-isopropyl-4-methylpyridin-3-yl)-4H-isochromeno[4,3-h]quinazolin-3(6H)-one

InChIKey: UWIDMHGDYVIUOQ-FQEVSTJZSA-N

SMILES: O=C1N(C2=C(N=CC=C2C)C(C)C)C3=C(OCC4=CC=CC=C45)C5=C(F)C=C3C(N6[C@H](CN(CC6)C(C=C)=O)C)=N1

Biological Activity: KRAS G12C inhibitor 23 is a KRAS G12C inhibitor. KRAS G12C inhibitor 23 inhibits H358 cells with an IC50 of 491 nM (WO2021218939A1, compound 1)[1].

Cat. No. Product Name Purity Description Pricing
HY-145020 		KRAS G12C inhibitor 23 KRAS G12C inhibitor 23 is a KRAS G12C inhibitor. KRAS G12C inhibitor 23 inhibits H358 cells with an IC50 of 491 nM (WO2021218939A1, compound 1).
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