2741870-21-1
Chemical Structure
RORγt inverse agonist 28
- CAS No.: 2741870-21-1
- Formula:C23H18Cl2F3NO5S
- Molecular Weight:548.36
IUPAC Name: (R)-N-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-3-hydroxy-2-(4-(methylsulfonyl)phenyl)propanamide
InChIKey: ZEYHCQNCNJXCAC-KRWDZBQOSA-N
SMILES: FC(F)(F)OC1=C(C2=C(C=C(C=C2Cl)NC([C@H](C3=CC=C(C=C3)S(C)(=O)=O)CO)=O)Cl)C=CC=C1
Biological Activity: RORγt inverse agonist 28 is a potent reverse agonist of RORγt. RORγt inverse agonist 28 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 28 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 6) [1].
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RORγt inverse agonist 28 | RORγt inverse agonist 28 is a potent reverse agonist of RORγt. RORγt inverse agonist 28 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 28 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 6) . | |||||||||||||||||||||
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Keywords